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What is gout?

Gout is a form of inflammatory arthritis which occurs when excess uric acid built up in the blood leads to inflammation in one or more joints. The big toe joint is most commonly affected.

How common is gout?

Around 224,000 (0.9%) people in Australia were estimated to be living with gout in 2022.

Impact of gout

  • Gout accounted for 0.7% of the total disease burden due to musculoskeletal conditions in 2023.
  • In 2020–21, an estimated $230.8 million was spent on the treatment and management of gout, representing 0.2% of total health system expenditure and 1.6% of expenditure for all musculoskeletal conditions.
  • Gout contributed to 573 deaths or 2.2 deaths per 100,000 population in 2022, representing 0.3% of all deaths. 

Treatment and management of gout

In 2021–22, there were 7,100 hospitalisations with a principal diagnosis of gout (27 per 100,000 population).

What is gout?

Gout is a form of inflammatory arthritis. It occurs when excess uric acid in the blood leads to deposits of uric acid crystals in one or more joints. These deposits cause inflammation, with the big toe joint being most commonly affected. Gout can also affect other joints in the arms (fingers, wrists, elbows) and legs (toes, ankles, knees).

Gout can be episodic (acute) or chronic. Acute gout is characterised by sudden attacks (flares) of severe pain, swelling, redness, heat, tenderness and stiffness in the affected joints. These flares can last for days or weeks and are followed by long periods without any symptoms. If flares occur in the same joint over many years, and the underlying excess of uric acid is not controlled, gout can become chronic.

What causes gout?

The underlying cause of gout is excess uric acid in the blood – a metabolic disorder called hyperuricaemia. This disorder is an independent risk factor for cardiovascular disease (Capuano et al. 2017) and metabolic syndrome (Ni et al. 2019; Wang et al. 2018).

Health risk factors for hyperuricaemia include obesity, diabetes, hypertension and heart disease, poor kidney function and kidney disease, and a diet high in meat, seafood and alcohol (Capuano et al. 2017; Ni et al. 2019; Wang et al. 2018).

How common is gout?

Around 224,000 (0.9%) people in Australia were estimated to be living with gout, according to self-reported data in the 2022 Australian Bureau of Statistics (ABS) National Health Survey (NHS) and the majority (75%) of people living with gout were male (ABS 2023).

While the self-reported prevalence of gout may be low, Australian population-based studies show variation for different population groups. A study of a general practice population found the prevalence of gout to be 1.5%. Prevalence was found to increase with age to 11% in men and 4.6% in women aged 85 and over (Robinson et al. 2015).

Impact of gout

Gout can have a significant impact on people’s lives including intense joint pain and swelling as well as functional impairment. Frequent attacks of gout have been found to be associated with reduction in work participation (De Meulemeester et al. 2020).

Measures of impact presented in this section include burden of disease, health expenditure and mortality data.

Burden of disease

In 2023, gout accounted for 0.1% of total disease burden (also known as disability adjusted life years or DALY), 0.2% of non-fatal burden (also known as ‘years lived with disability’ or YLD), and less than 0.01% of fatal burden (also known as years of life lost, or YLL). Within the musculoskeletal disease group, gout accounted for 0.7% of total burden (DALY) (AIHW 2023a).

After adjusting for different population age structures over time, the rate of gout burden halved from 0.35 to 0.17 DALY per 1,000 population between 2003 and 2023 (Figure 1). For more information, see the Australian Burden of Disease Study 2023. 

Figure 1: Burden of disease due to gout, by age and sex, 2003, 2011, 2015, 2018 and 2023

This figure shows that the burden of gout was greater in males compared with females. 

Health system expenditure

In 2020–21, an estimated $230.8 million of expenditure in the Australian health system was attributed to gout, representing 0.2% of total health system expenditure and 1.6% of expenditure for all musculoskeletal conditions (AIHW 2023b).

The distribution of health system expenditure on gout by age and sex reflects the prevalence distribution, with spending concentrated amongst older age groups and males.

For more information, see Health system spending on disease and injury in Australia, 2020–21.

How many deaths were associated with gout?

Gout was recorded as an underlying and/or associated cause for 573 deaths or 2.2 deaths per 100,000 population in Australia in 2022. This represented 0.3% of all deaths and 5.5% of all musculoskeletal deaths.

Gout was the underlying cause for 34 deaths (5.9% of gout deaths) and an associated cause only, for 539 deaths (94% of gout deaths).

After adjusting for different population age structures over time, gout mortality rates (underlying and/or associated cause) changed little between 2012 and 2022 (1.4 and 1.6 per 100,000 population, respectively).

Treatment and management of gout

Gout can be managed or even prevented by long-term therapy with medications and lifestyle changes to control hyperuricaemia and reduce levels of uric acid in the body.

Gout can be controlled with early and ongoing treatment, including:

  • establishing a definitive diagnosis
  • providing rapid pain relief for flares
  • preventing flares and complications (Graf et al. 2015; Ragab et al. 2017; Richette et al. 2016).

Flares and complications can be managed by reducing risk factors for hyperuricaemia (dehydration, obesity and alcohol intake), taking urate-lowering medications to keep uric acid levels low, and managing comorbid conditions, such as high blood pressure, chronic kidney disease, diabetes and heart disease (Ragab et al. 2017).

The use of non-steroidal anti-inflammatory drugs (NSAIDs), low-dose colchicine and oral/intra-muscular/intra-articular glucocorticoids has also been found to be effective in managing acute gout (Graf et al. 2015; Richette et al. 2016).

What role do hospitals play in treating gout?

People with gout may require admission to hospital when they experience sudden attacks (flares) of severe pain, swelling, redness, heat, tenderness and stiffness in the affected joints. These flares can last for days or weeks and are followed by long periods without any symptoms.

Data from the National Hospital Morbidity Database (NHMD) show that in 2021–22, there were 21,700 hospitalisations with a principal or additional diagnosis (any diagnosis) of gout, representing 0.2% of all hospitalisations.

The rest of this section discusses hospitalisations with a principal diagnosis of gout, unless otherwise stated. However, charts and tables also include statistics for any diagnosis of gout.

In 2021–22:

  • there were 7,100 hospitalisations, representing 0.1% of all hospitalisations and 27 hospitalisations per 100,000 population
  • gout accounted for 29,500 bed days, representing 0.1% of all bed days
  • 77% of gout hospitalisations were overnight stays, with an average length of 5.1 days (Figure 2).

Variation by age and sex

In 2021–22, gout hospitalisation rates:

  • increased with increasing age and were highest for people aged 85 and over (210 per 100,000 population)
  • were 3.7 times as high for males compared with females (43 and 12 per 100,000 population, respectively) (Figure 2).

Trends over time

Between 2011–12 and 2021–22, gout hospitalisation rates remained stable (25 to 27 per 100,000 population).

Figure 2: Age distribution for gout hospitalisations, by sex, 2021–22

This figure shows the average length of overnight hospitalisations for people aged 85 and over with a principal diagnosis of gout was almost 7 days.

Data